Reactive oxygen species associated molecular signature predicts survival in Septic Patients

Background: Sepsis syndrome’s mortality rate is 26% to 82% depending on whether septicshock occurs. Currently there are no reliable diagnostic biomarkers available to predictsurvival of patients with sepsis. Furthermore, researchers at the University of Arizonaunderstand there is evidence indicating oxidative stress plays a role in the pathogenesis of sepsis.

Invention: The technology is a 21-gene reactive oxygen species (ROS)-associated molecularsignature that predicts survival in septic patients.  

Applications:·Diagnostic tool and/or service for patients with sepsis 

Advantages:

·Traditional biomarkers (C-reactive protein, interleukin-6, procalcitonin) are not reliable inpredicting survival

·ROS-associated biomarkers were shown to predict the odds of patient's outcome